Bournemouth will host Manchester City in the FA Cup quarter-finals, while Fulham’s reward for knocking out holders Manchester United is a home London derby with Crystal Palace.
Sky Bet Championship side Preston, the lowest-ranked team left in the competition, will be at home to Aston Villa.
Brighton, having beaten Newcastle 2-1 after extra-time at St James’ Park on Sunday, will take on either Nottingham Forest or Ipswich, who play on Monday night, at the Amex Stadium.
The quarter-final ties will take place across the final weekend of March.
FA Cup quarter-finals draw:
Ties to be played across the weekend of March 29/30:
Fulham vs Crystal Palace
Preston North End vs Aston Villa
Bournemouth vs Manchester City
Brighton vs Nottingham Forest or Ipswich